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Index > Protein center > Pfn2(Gene name) > Mouse
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  • Pfn2 (Gene name),
  • Profilin-2 (Protein name ),  PROF2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Pfn2;
    Protein name:
    Profilin-2;
    Alternative:
    Profilin II;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio.
    Function:
    Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
    Subcellular Location:
    Cytoplasm cytoskeleton
    Protein Attributes:
    Sequence length:
    140
    Sequence:
    50:
    MAGWQSYVDN | LMCDGCCQEA | AIVGYCDAKY | VWAATAGGVF | QSITPVEIDM | 
    100:
    IVGKDREGFF | TNGLTLGAKK | CSVIRDSLYV | DGDCTMDIRT | KSQGGEPTYN | 
    140:
    VAVGRAGRVL | VFVMGKEGVH | GGGLNKKAYS | MAKYLRDSGF | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    String:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Profilin-2
    Cat.:
    E0347h
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    Packing:
    96T
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    ELISA Kit for Mouse Profilin-2
    Cat.:
    E0347r
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse Profilin-2
    Cat.:
    E0347b
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse Profilin-2
    Cat.:
    E0347m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Profilin-2
    Cat.:
    U0347h
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Profilin-2
    Cat.:
    U0347m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Profilin-2
    Cat.:
    U0347b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Profilin-2
    Cat.:
    U0347r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Profilin-2
    Cat.:
    P0347Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Profilin-2
    Cat.:
    P0347Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Profilin-2
    Polyclonal Antibody for Mouse Profilin-2
    Cat.:
    P0347Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Profilin-2
    Monoclonal Antibody for Mouse Profilin-2
    Monoclonal Antibody for Mouse Profilin-2
    Monoclonal Antibody for Mouse Profilin-2
    Protein for Mouse Profilin-2
    Protein for Mouse Profilin-2
    Protein for Mouse Profilin-2
    Protein for Mouse Profilin-2

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    Linearity
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    References
    1. 1.
      "Alternative splicing of the mouse profilin II gene generates functionally different profilin isoforms."
      Di Nardo A. , Gareus R. , Kwiatkowski D. , Witke W.
      J. Cell Sci.113:3795-3803(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
    2. 2.
      "Profilin II is alternatively spliced, resulting in profilin isoforms that are differentially expressed and have distinct biochemical properties."
      Lambrechts A. , Braun A. , Jonckheere V. , Aszodi A. , Lanier L.M. , Robbens J. , Van Colen I. , Vandekerckhove J. , Faessler R. , Ampe C.
      Mol. Cell. Biol.20:8209-8219(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3)
      strain: C57BL/6J.
      tissue: Hippocampus.
      tissue: Testis.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    5. 5.
      Lubec G. , Klug S.
      Submitted (2007-03) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 55-69; 76-89 AND 92-105;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Hippocampus.
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